BDBM50245444 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrimidine-5-carbonitrile::CHEMBL500591

SMILES Nc1ncnc(Nc2ccc(OCc3ccccc3)c(Cl)c2)c1C#N

InChI Key InChIKey=DNJLGPOTNUZJMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245444   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50245444(4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrim...)
Affinity DataIC50: 27nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50245444(4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrim...)
Affinity DataIC50: 470nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed