BDBM50245577 CHEMBL4067592

SMILES CC1(C)OCCN(C1=O)c1cccc(c1)-c1cc(Cl)c2c(N)ncnn12

InChI Key InChIKey=QNKJDNOTCJIIQY-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245577   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245577(CHEMBL4067592)Copy SMILESCopy InChI

Affinity DataIC50: 7.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245577(CHEMBL4067592)Copy SMILESCopy InChI

Affinity DataIC50: 130nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245577(CHEMBL4067592)Copy SMILESCopy InChI

Affinity DataIC50: 610nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL