BDBM50245584 CHEMBL4089756

SMILES COc1ccc(cc1N1CCOC(C)(C)C1=O)-c1cc(-c2ccnn2CC(F)(F)F)c2c(N)ncnn12

InChI Key InChIKey=UNPYBTUGNSSBGS-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245584   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245584(CHEMBL4089756)Copy SMILESCopy InChI

Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245584(CHEMBL4089756)Copy SMILESCopy InChI

Affinity DataIC50: 29nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50245584(CHEMBL4089756)Copy SMILESCopy InChI

Affinity DataIC50: 630nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL