BDBM50245585 CHEMBL4072098

SMILES C[C@H]1CN(C(=O)C(C)(C)O1)c1cc(ccc1C#N)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=QBZJCJNDEWAZNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245585   

LigandPNGBDBM50245585(CHEMBL4072098)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50245585(CHEMBL4072098)
Affinity DataIC50: 44nMAssay Description:Inhibition of PI3Kdelta in ACD-treated human whole blood assessed as reduction in CD69 expression measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50245585(CHEMBL4072098)
Affinity DataIC50: 120nMAssay Description:Inhibition of PI3Kdelta in ACD-treated human whole blood assessed as reduction in IFNgammaX production measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed