BDBM50245868 4-(2-(6-methoxy-3,4-dihydro-2H-chromen-3-yl)benzo[d]oxazol-6-yl)pyrimidin-2-amine::CHEMBL461338

SMILES COc1ccc2OCC(Cc2c1)c1nc2ccc(cc2o1)-c1ccnc(N)n1

InChI Key InChIKey=PZWKXWPMVNKURA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245868   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50245868(4-(2-(6-methoxy-3,4-dihydro-2H-chromen-3-yl)benzo[...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50245868(4-(2-(6-methoxy-3,4-dihydro-2H-chromen-3-yl)benzo[...)
Affinity DataIC50: 46nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed