BDBM50246014 (1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylamino)methyl)-2,3-dihydro-1H-inden-2-ol::CHEMBL454770

SMILES CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccc(O)cc1C

InChI Key InChIKey=JZKRUQHCKJXZSS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246014   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50: 4nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50: 14nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed