BDBM50246272 (S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanoate::CHEMBL488255

SMILES COC(=O)[C@H](C)n1c2c(C)cc(C)cc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O

InChI Key InChIKey=BSJYDQGLLSLMFP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246272   

LigandPNGBDBM50246272((S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246272((S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-...)
Affinity DataIC50: 72nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed