BDBM50246409 CHEMBL455658::N-(4-(1H-pyrazol-4-yl)phenyl)-3,4-dihydro-2H-chromene-3-carboxamide::N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide

SMILES O=C(Nc1ccc(cc1)-c1cn[nH]c1)C1COc2ccccc2C1

InChI Key InChIKey=JJJJNDXIYADPOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246409   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50246409(N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide...)
Affinity DataIC50: 25nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50246409(N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50246409(N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50246409(N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide...)
Affinity DataIC50: 25nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed