BDBM50246421 (R)-N,N-dimethyl-4-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanamide::CHEMBL455670

SMILES CN(C)C(=O)CCCn1c2ccccc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O

InChI Key InChIKey=YYWRTYIKIIRBJZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246421   

LigandPNGBDBM50246421((R)-N,N-dimethyl-4-(3-(2-(3-methyl-2,5-dioxo-1',3'...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246421((R)-N,N-dimethyl-4-(3-(2-(3-methyl-2,5-dioxo-1',3'...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50246421((R)-N,N-dimethyl-4-(3-(2-(3-methyl-2,5-dioxo-1',3'...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed