BDBM50246453 (rel)-8-(bis(2-chlorophenyl)methyl)-3-phenyl-3-(pyrrolidin-1-ylmethyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL453648

SMILES Clc1ccccc1C(N1[C@H]2CC[C@H]1CC(CN1CCCC1)(C2)c1ccccc1)c1ccccc1Cl

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246453   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50246453((rel)-8-(bis(2-chlorophenyl)methyl)-3-phenyl-3-(py...)
Affinity DataKi:  70nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human cloned nociceptin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50246453((rel)-8-(bis(2-chlorophenyl)methyl)-3-phenyl-3-(py...)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed