BDBM50246489 CHEMBL4091441

SMILES Cc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1

InChI Key InChIKey=VPVLPCIBKVWFDT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246489   

TargetALK tyrosine kinase receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246489(CHEMBL4091441)
Affinity DataIC50: 50nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246489(CHEMBL4091441)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of human ERG by fluorescently labeled tracer binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2019
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50246489(CHEMBL4091441)
Affinity DataEC50:  21nMAssay Description:Inhibition of human RIPK3 using MBP as substrate by [gamma33-ATP] based radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed