BDBM50246571 4-(4-hydroxyphenyl)-6,7-dimethoxy-2H-pyrido[3,4-b]indol-1(9H)-one::CHEMBL461162

SMILES COc1cc2[nH]c3c(=O)[nH]cc(-c4ccc(O)cc4)c3c2cc1OC

InChI Key InChIKey=MKOGRTXXHLJYQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246571   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Universita Di Milano

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246571BDBM50246571(4-(4-hydroxyphenyl)-6,7-dimethoxy-2H-pyrido[3,4-b]...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant RET active protein by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed