BDBM50246755 CHEMBL450479::N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoyl)-ethylcarbamoyl]-5-methylhexanoyl}-N-dodecansulfonylhydrazide

SMILES CCCCCCCCCCCCS(=O)(=O)NNC(=O)C[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC

InChI Key InChIKey=PCUZNOWAYFCVHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246755   

TargetMatrix metalloproteinase-14(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246755(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246755(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246755(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed