BDBM50246791 CHEMBL498915::N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoyl)-ethylcarbamoyl]-5-methylhexanoyl}-N-(4-succinimidyl)-benzenesulfonylhydrazide

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NNS(=O)(=O)c1ccc(cc1)-n1c(O)ccc1O

InChI Key InChIKey=DUONGMKIDQRGNH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50246791   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant pro-MMP7 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246791(N'-{3-(R)-[2-(S)-(1H-Indol-3-yl)-1-(methylcarbamoy...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed