BDBM50246796 CHEMBL509346::N'-{3-(E)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methylcarbamoyl)-ethylcarbamoyl]-6-phenylhexenoyl}-N-4-(4-bromophenyl)benzenesulfonylhydrazide

SMILES CNC(=O)[C@H](Cc1c([nH]c2ccccc12)-c1ccccc1)NC(=O)C(CC(=O)NNS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)=CCCc1ccccc1

InChI Key InChIKey=QEEFWEXKMRZIRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246796   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246796(N'-{3-(E)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 827nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246796(N'-{3-(E)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 463nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246796(N'-{3-(E)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246796(N'-{3-(E)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed