BDBM50246797 CHEMBL502674::N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methylcarbamoyl)-ethylcarbamoyl]-5-methylhexanoyl}-N-4-(4-bromophenyl)benzenesulfonylhydrazide

SMILES CNC(=O)[C@H](Cc1c([nH]c2ccccc12)-c1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NNS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1

InChI Key InChIKey=MLPPJTCCWGPRTB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50246797   

TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246797(N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246797(N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246797(N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246797(N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50246797(N'-{3-(R)-[2-(S)-(2-Phenyl-1H-indol-3-yl)-1-(methy...)
Affinity DataIC50: 247nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed