BDBM50246829 CHEMBL70624

SMILES NC1=NCCN1Cc1cccnc1

InChI Key InChIKey=ZCDGHEWSWOTSGZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246829   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50246829(CHEMBL70624)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50246829(CHEMBL70624)
Affinity DataKi:  3.75E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246829(CHEMBL70624)
Affinity DataKi:  9.89E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed