BDBM50246901 CHEMBL4074539

SMILES FC(F)(F)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(cc3)N3CCOCC3)cc2C#N)ccc1Cl

InChI Key InChIKey=QIEDVVRURQFSEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246901   

TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246901(CHEMBL4074539)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed