BDBM50246921 CHEMBL4077043

SMILES COC(c1cc(Cl)c2CCN(Cc3c(OC)cc(C)[nH]c3=O)C(=O)c2c1Cl)C1(C)COC1

InChI Key InChIKey=MCMKAVXRKBSUCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246921   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50246921(CHEMBL4077043)
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50246921(CHEMBL4077043)
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed