BDBM50248289 5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-1-phenyl-1H-1,2,3-triazole-4-carboxylic acid::CHEMBL514173

SMILES Cc1oc(nc1CCOc1cccc(Cc2c(nnn2-c2ccccc2)C(O)=O)c1)-c1ccccc1

InChI Key InChIKey=MBBAYLYCJKYLOJ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248289   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248289(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50: >1.50E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248289(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50: 750nMAssay Description:Binding affinity to PPARgamma by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248289(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Binding affinity to PPARalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248289(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50:  7.90E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed