BDBM50248293 CHEMBL473556::N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc2ncnc(Nc3ccc(cc3)-c3nc4ccccc4s3)c2cc1OC

InChI Key InChIKey=CCIYHYFLYIQCJR-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50248293   

TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 135nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 135nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248293(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxyqu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed