BDBM50248389 2-amino-N-(4-methylthiazol-2-yl)-5-(pyridin-2-ylthio)benzamide::CHEMBL523602

SMILES Cc1csc(NC(=O)c2cc(Sc3ccccn3)ccc2N)n1

InChI Key InChIKey=XGWOVHWNRPREDT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248389   

TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248389(2-amino-N-(4-methylthiazol-2-yl)-5-(pyridin-2-ylth...)
Affinity DataEC50:  220nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248389(2-amino-N-(4-methylthiazol-2-yl)-5-(pyridin-2-ylth...)
Affinity DataEC50:  1.20E+3nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed