BDBM50248579 1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)pyrrolidine-3-carboxylic acid::CHEMBL465957

SMILES OC(=O)C1CCN(C1)c1ccc(cn1)C(=O)Nc1nc(cs1)-c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=QHDHUEIPKWBLKG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248579   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248579(1-(5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazo...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed