BDBM50248695 3-({2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl}amino)-3-methyl-N-[(1S,2R)-2-(3-chlorophenyl)cyclopropyl]butanamide::CHEMBL463231

SMILES CC(C)(CC(=O)N[C@H]1C[C@@H]1c1cccc(Cl)c1)NCC(=O)N1CC(F)(F)C[C@H]1C#N

InChI Key InChIKey=BTGXNIALOLYGDP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248695   

TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248695(3-({2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248695(3-({2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248695(3-({2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248695(3-({2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed