BDBM50248878 5,6-Dimethoxy-2-{4-[(pyrrolidin-1-yl)methyl] benzyl}-benzofuran-3(2H)-one::CHEMBL515241

SMILES COc1cc2oc(Cc3ccc(CN4CCCC4)cc3)c(O)c2cc1OC

InChI Key InChIKey=FXDZOVUDEYSNOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248878   

TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248878(5,6-Dimethoxy-2-{4-[(pyrrolidin-1-yl)methyl] benzy...)
Affinity DataIC50: 620nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248878(5,6-Dimethoxy-2-{4-[(pyrrolidin-1-yl)methyl] benzy...)
Affinity DataIC50: 4.98E+4nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed