BDBM50249029 CHEMBL4088300

SMILES CC(C)n1nc(-c2cc(CO)on2)c2c(N)ncnc12

InChI Key InChIKey=OHYRYMSOCVIPCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249029   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50249029(CHEMBL4088300)
Affinity DataIC50: 10nMAssay Description:Inhibition of human RET kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50249029(CHEMBL4088300)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant RET (unknown origin) using poly (Glu,Tyr) 4:1 substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed