BDBM50249072 CHEMBL4073305

SMILES CC(C)(O)c1cncc(c1)-n1ncc2cc(ccc12)C(F)(F)F

InChI Key InChIKey=QHEFMLSTXVFBKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249072   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249072(CHEMBL4073305)
Affinity DataIC50: 507nMAssay Description:Inhibition of human CYP11B2-CLE9 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249072(CHEMBL4073305)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed