BDBM50249150 8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide::CHEMBL474189
SMILES CC1(CC2(C)c3ccccc3C1c1ccccc21)C(=O)Nc1nccs1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50249150
Affinity DataKi: 1nMAssay Description:Displacement of GS-red from glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in IL-1beta-stimulated human A549 cells assessed as inhibition of NFkappaB-dependent E-sele...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Transrepression activity at glucocorticoid receptor alpha in phorbol myristate acetate-stimulated human A549 cells assessed as inhibition of AP1 resp...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 14.7nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataEC50: 14.7nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of radioligand from progesterone receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 117nMAssay Description:Transactivation activity at GR-alpha in human NP1 Hela cells assessed as induction of GAL4-DBD after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 117nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 121nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of radioligand from androgen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of radioligand from estrogen receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair