BDBM50249157 CHEMBL4071221

SMILES Cc1nsc(n1)N1CCC2(C1)CCN(C[C@H](O)c1ccc3C(=O)OCc3c1C)CC2

InChI Key InChIKey=YFWDNFXIXONSOG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249157   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50249157(CHEMBL4071221)Copy SMILESCopy InChI

Affinity DataIC50: 250nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/16/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50249157(CHEMBL4071221)Copy SMILESCopy InChI

Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/16/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL