BDBM50249241 CHEMBL4092262

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CCN(C2=O)c2ccncc2)CC1

InChI Key InChIKey=RSXZHMMKTWSARQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249241   

LigandPNGBDBM50249241(CHEMBL4092262)
Affinity DataIC50: 11nMAssay Description:Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50249241(CHEMBL4092262)
Affinity DataIC50: 64nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50249241(CHEMBL4092262)
Affinity DataIC50: 1.04E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50249241(CHEMBL4092262)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of human ERG by Qpatch electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed