BDBM50249274 CHEMBL4093121

SMILES CCn1nc(ccc1=O)N1CCC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C1=O

InChI Key InChIKey=VDCAXVPVBQTWQU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249274   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50249274(CHEMBL4093121)Copy SMILESCopy InChI

Affinity DataIC50: 77nMAssay Description:Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/16/2019
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50249274(CHEMBL4093121)Copy SMILESCopy InChI

Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/16/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL