BDBM50249336 CHEMBL1910509

SMILES O=C1NC(=O)\C(S1)=C\c1c[nH]c2ccccc12

InChI Key InChIKey=YRPCEGFPKMQCHL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249336   

TargetPoly [ADP-ribose] polymerase 1(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249336(CHEMBL1910509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP1 (unknown origin) using activated DNA as substrate measured after 60 mins in presence of biotinylated NAD by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2019
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249336(CHEMBL1910509)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) using GS-2 peptide substrate incubated for 30 mins by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249336(CHEMBL1910509)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50249336(CHEMBL1910509)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of recombinant human His6-taged GSK-3beta assessed as substrate phosphorylation incubated for 30 mins using RRRPASVPPSPSLSRHSSHQRR peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed