BDBM50249598 CHEMBL1773422

SMILES C[S+]([O-])c1nc(c(-c2ccnc(NC(C)=O)c2)n1C)-c1ccc(F)cc1

InChI Key InChIKey=DRMJRHUMYBYDIX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50249598   

TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by beta-galactosidase enzyme complementation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 710nMAssay Description:Inhibition of P38 MAPKalpha in LPS-stimulated human whole blood assessed as decrease in TNFalpha levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 800nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human PDE4A4 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human PDE4C1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 2.13E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed