BDBM50249605 3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinolin-4(1H)-one::CHEMBL470707

SMILES CC(=O)c1c(Nc2ccc(Br)cc2)nc2c(Br)ccc(Br)c2c1O

InChI Key InChIKey=KMZAXCJSAFYPSE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50249605   

TargetProcathepsin L(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human liver cathepsin L after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain by fluorometric assay using pep2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain after 30 mins by fluorometric assay using pep1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 9.18E+4nMAssay Description:Inhibition of human liver cathepsin H after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249605(3-acetyl-5,8-dibromo-2-(4-bromophenylamino)quinoli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human liver cathepsin D after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed