BDBM50249660 3-acetyl-8-chloro-2-(4-chloro-2-fluorophenylamino)-5-methylquinolin-4(1H)-one::CHEMBL491899

SMILES CC(=O)c1c(O)c2c(C)ccc(Cl)c2nc1Nc1ccc(Cl)cc1F

InChI Key InChIKey=ZOKOBEQQPDPBLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249660   

TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249660(3-acetyl-8-chloro-2-(4-chloro-2-fluorophenylamino)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human erythrocytes mu-calpain after 30 mins by fluorometric assay using pep1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed