BDBM50249736 CHEMBL491937::benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-ylamino)-1-oxo-3-phenylpropan-2-ylcarbamate

SMILES FCC(=O)C(Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=CAILNONEKASNSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249736   

TargetCathepsin B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249736(benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-y...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249736(benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-y...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human liver cathepsin L after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249736(benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human liver cathepsin H after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50249736(benzyl (S)-1-((S)-4-fluoro-3-oxo-1-phenylbutan-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human liver cathepsin D after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed