BDBM50249802 CHEMBL4791182

SMILES CCn1cc(C(O)=O)c(=O)c2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc12

InChI Key InChIKey=YWJJMGOABBHKMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249802   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50249802(CHEMBL4791182)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as conversion of NADH to NAD+ by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50249802(CHEMBL4791182)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase using biotinylated oligonucleotide as substrate incubated for 30 mins in presence of ATP by fluorescence-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed