BDBM50250215 CHEMBL4091536

SMILES CC[C@@H](C)[C@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cn2cc(C[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCSC)C(O)=O)nn2)NC(=O)[C@@H](N)CCCCN

InChI Key InChIKey=PXAABUPNKZZNCO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250215   

TargetMelanocortin receptor 5(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250215(CHEMBL4091536)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at EYFP-fused human MC5R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250215(CHEMBL4091536)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250215(CHEMBL4091536)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at EYFP-fused human MC3R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250215(CHEMBL4091536)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by luminescent enzymatic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed