BDBM50250257 CHEMBL4096438

SMILES Clc1ccncc1C(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=BJPUHOBDEBHQRV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50250257   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250257(CHEMBL4096438)
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed