BDBM50250269 CHEMBL4077271

SMILES Clc1ccc(C(=O)NC2CCN(Cc3c[nH]c4ccccc34)CC2)c(Cl)n1

InChI Key InChIKey=CRWOMNWHLXXELU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250269   

TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250269(CHEMBL4077271)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250269(CHEMBL4077271)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250269(CHEMBL4077271)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250269(CHEMBL4077271)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250269(CHEMBL4077271)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed