BDBM50250857 CHEMBL4081625

SMILES FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F

InChI Key InChIKey=GNGJOXRYUALUAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250857   

TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250857(CHEMBL4081625)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2019
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250857(CHEMBL4081625)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2019
Entry Details Article
PubMed