BDBM50250932 CHEMBL465251::demethylzeylasterone

SMILES C[C@]12CC[C@](C)(C[C@H]1[C@]1(C)CC[C@]3(C)C(=CC(=O)c4c3cc(O)c(O)c4C(O)=O)[C@@]1(C)CC2)C(O)=O

InChI Key InChIKey=IGEUWSSSLAVCIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50250932   

TargetDNA topoisomerase 2-alpha(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250932(demethylzeylasterone | CHEMBL465251)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of human topoisomerase 2 p170alpha assessed as relaxation of lambda ZAPII plasmid Bluescript KS+ DNA by SDS electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed