BDBM50250939 CHEMBL4066961

SMILES COCCCc1ccc2oc(cc2c1)-c1ccc(OC)c(OC)c1

InChI Key InChIKey=CUEPJIGXQLIOIK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50250939   

TargetCytochrome P450 2C8(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Medifron Dbt

Curated by ChEMBL
LigandPNGBDBM50250939(CHEMBL4066961)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed