BDBM50250940 CHEMBL4074910

SMILES CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc(O)cc1

InChI Key InChIKey=YBTWUDMFWKOPHT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250940   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Progenra

Curated by ChEMBL
LigandPNGBDBM50250940(CHEMBL4074910)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Progenra

Curated by ChEMBL
LigandPNGBDBM50250940(CHEMBL4074910)
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Progenra

Curated by ChEMBL
LigandPNGBDBM50250940(CHEMBL4074910)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Progenra

Curated by ChEMBL
LigandPNGBDBM50250940(CHEMBL4074910)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho110 as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Progenra

Curated by ChEMBL
LigandPNGBDBM50250940(CHEMBL4074910)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed