BDBM50250942 CHEMBL4076471

SMILES CC(C)c1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc(O)cc1

InChI Key InChIKey=JCAFDYJPKPNYIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250942   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50250942(CHEMBL4076471)
Affinity DataIC50: 2.14E+4nMAssay Description:Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50250942(CHEMBL4076471)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50250942(CHEMBL4076471)
Affinity DataIC50: 1.97E+5nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho110 as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed