BDBM50250967 CHEMBL4061087::US10688093, Compound 382_7249_0081::US11701353, Compound 382_7249_0081

SMILES CC(=O)Nc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(O)cc1

InChI Key InChIKey=KBDXKGGQZIHXGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250967   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50250967(CHEMBL4061087 | US10688093, Compound 382_7249_0081...)
Affinity DataIC50: 1.51E+4nMAssay Description:Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50250967(CHEMBL4061087 | US10688093, Compound 382_7249_0081...)
Affinity DataIC50: 838nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50250967(CHEMBL4061087 | US10688093, Compound 382_7249_0081...)
Affinity DataIC50: 898nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent