BDBM50251650 CHEMBL4099902

SMILES Cc1c(c(CN2CCCCC2)nn1C)-c1cccc2c(CCCOc3cc(C)c(Cl)c(C)c3)c([nH]c12)C(O)=O

InChI Key InChIKey=GSXVVMUSIZPWMH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251650   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251650(CHEMBL4099902)
Affinity DataKi:  22nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251650(CHEMBL4099902)
Affinity DataKi:  73nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed