BDBM50251744 CHEMBL481672::endo-4-(2-(3-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)-8-aza-bicyclo[3.2.1]octan-8-yl)ethyl)benzoic acid

SMILES OC(=O)c1ccc(CCN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251744   

TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251744(endo-4-(2-(3-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)
Affinity DataIC50: 1nMAssay Description:Inhibition of LTA4 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251744(endo-4-(2-(3-(4-(4-(oxazol-2-yl)phenoxy)phenylamin...)
Affinity DataIC50: 40nMAssay Description:Inhibition of LTA4 hydrolase in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed