BDBM50251870 CHEMBL481353::N,N-dimethyl(2-(4-(trifluoromethoxy)phenoxy)phenyl)methanamine

SMILES CN(C)Cc1ccccc1Oc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=YZFBWQVFTDRJGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251870   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251870(N,N-dimethyl(2-(4-(trifluoromethoxy)phenoxy)phenyl...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50251870(N,N-dimethyl(2-(4-(trifluoromethoxy)phenoxy)phenyl...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251870(N,N-dimethyl(2-(4-(trifluoromethoxy)phenoxy)phenyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed