BDBM50252020 (5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N,N-dimethylmethanamine::CHEMBL451120

SMILES CSc1ccc(Oc2ccc(Br)cc2CN(C)C)cc1

InChI Key InChIKey=WPGUQXCZGQYNLZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252020   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252020((5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N,N-dime...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252020((5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N,N-dime...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252020((5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N,N-dime...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed